5 days is a good amount of time in the Mawlamyine/Mon State/Karen State region and you will be able to see much that is on offer without rushing around, though there will still be some choices to be made.
Walk Lower Main Rd and Strand Road. Check out the architecture and get a feel for the area.
Yadanarbon (Queen’s) Monastery
Watch the sunset from the view point
Optional extra if you’re feeling energetic: Mukyi jungle walk to see newly discovered rock carvings and overnight at Mukyi Meditation Retreat .
Sunset cruise or Strand Road walk
Option 1: Adventure
Option 2: Culture